Since the outbreak of COVID-19, governments worldwide have invested enormous resources in scaling up their testing capacity. PCR testing is the most reliable test method, but it can take several hours to a few days to deliver test results, leaving a window in which infection may spread. Olfert Landt, CEO of TIB Molbiol, identified the need for a shorter lead time and came up with the idea to develop a continuous PCR test machine. Samples are not moved through the testing process in batches as is normally done, but one by one, reducing the total testing time significantly.
Challenges
To develop an automated machine that can evaluate the tests, TIB Molbiol needed a technology partner who could help them face, several challenges, including a tight time schedule, lack of access to equipment, and ability to perform precise project work with robotics, chemicals, and small components.
Solution
After figuring out an overall concept for the realization of the project, technology reviews, and parameter studies, DIS/CREADIS and TIB Molbiol collaborated to develop an automated PCR test machine that delivers test results in less than one hour. The machine has a total output of 60 tests per hour and machine. The automated testing combined with the gargling test method promised to bring real progress in the fight against the COVID-19 pandemic.
The solution not only reduced the demand for trained personnel but also brought advantages in availability and price. Unlike tests relying on a specific cartridge, this solution required fewer and much more general, expendable items. The recurring costs per test are, therefore, significantly lower, and availability is easier to ensure. With these characteristics and the mobility of the solution, many new use cases like on-site testing for public events become conceivable, and returning to a normal life comes closer.
FACTS
How we collaborate
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The collaboration of an agile automation expert like DIS/CREADIS and a science company with deep knowledge in molecular biology and PCR testing such as TIB Molbiol made the project a success. DIS/CREADIS project manager Jannick Schulte praised the collaboration and outcome, saying, “The past couple of months have been extremely focused and exciting. Regardless of the many challenges, everything has been solved state-of-the-art thanks to innovative thinking and pragmatic solutions. All in all, it has been an experience of coming together as tech partners with a project goal and finding solutions that can make a true difference.“
How we collaborate
<<
The collaboration of an agile automation expert like DIS/CREADIS and a science company with deep knowledge in molecular biology and PCR testing such as TIB Molbiol made the project a success. DIS/CREADIS project manager Jannick Schulte praised the collaboration and outcome, saying, “The past couple of months have been extremely focused and exciting. Regardless of the many challenges, everything has been solved state-of-the-art thanks to innovative thinking and pragmatic solutions. All in all, it has been an experience of coming together as tech partners with a project goal and finding solutions that can make a true difference.“
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